Association of mean platelet volume in patients with acute coronary syndrome: A Case control study

Background: Ischemic Heart Diseases are the leading cause of morbidity and mortality worldwide. In comparison with the people of European ancestry, CVD affects Indians at least a decade earlier and in their most productive midlife. Nearly two-thirds of the burden of NCD mortality in India is currently contributed by CVD-related conditions. Platelet hyper-reactivity and local platelet activation have been suggested to play a crucial role in acute coronary events (including ACS). Objectives: So this study was undertaken to determine the association of MPV in patients with ACS in relation to various types. Methods: This study is under taken among 70 ACS patients admitted and compared with 70 controls, after excluding the patients affected by diseases which are known to alter platelets structure and function. Results: The mean age of the patients among cases was found to be 64.8±10.8 years and 61.9±10.6 years among controls (p value– 0.11). On comparing, MPV was found to be 8.9±0.9 fL in control and was 12±1.4, 11.5±1.2, 10.3±0.8 fL among STEMI, NSTEMI and Unstable Angina patients respectively (p value<0.001). Conclusion: MPV is significantly higher in (ACS) cases compared to control group, among cases it was significantly high in STEMI, followed by NSTEMI and Unstable Angina. Platelet Indices help in anticipating severity (risk stratification) of CAD and also may help in diagnosis ACS patients, where myocardial injury markers are not available

Study the prognostic significance of various biochemical parameters in organophosphorus poisoning

Background: Acute organophosphorus poisoning is an important cause of morbidity and mortality in developing countries like India. Objective: To study clinical features and biochemical parameters in patients admitted with acute organophosphorus poisoning and to determine use of these biochemical marker in prediction of severity of acute OP poisoning. Material and method: 94 cases of OP poisoning admitted to KIMS Hospital, Hubbali between January 1st 2017 to December 31th 2017 were studied. Results: OP poisoning is more common in adults of age group between 20 – 30 years, Incidence is was more in male patients, Mortality rate is 12.8%. Mean values of Serum amylase, serum LDH, serum CPK and serum creatinine were negatively correlated with pseudcholinesterase levels and it was statistically significant. correlation between the severity of OP poisoning (based on Peradenyia score) and biochemical parameters like pseudocholinesterase, serum amylase, serum CPK, serum LDH, RBS was statistically significant. But Serum Creatinine levels did not show statistically significant correlation. Conclusions: The correlation between the severity of OP poisoning and biochemical parameterswas statistically significant and they are usefull in predicting development of respiratory failure

Resistance and wash measurements on a series of high speed displacement monohull and catamaran forms in shallow water

The paper summarises an experimental investigation into the resistance and wash waves of high speed displacement monohulls and catamarans in shallow water.Measurements of total resistance, running trim, sinkage and multiple longitudinal wave cuts were carried out for three round bilge hulls derived from the NPL series and one from Series 64. Parametric changes included length/displacement ratios of 7.4, 8.5 and 9.5, and hull separation/length ratios of 0.2, 0.4 and infinity. The tests were carried out in two depths of shallow water over a length Froude Number range of 0.25 to 1.0 and a depth Froude Number range of 0.5 to 3.0. The wave resistance was derived using wave pattern analysis and the principal particulars of the generated wave system are presented as maximum wave height, period, distribution of energy and direction of wave propagation.The results of the investigation provide a better understanding of the performance of high speed displacement monohulls and catamarans in shallow water, including the influences of speed, water depth, hull separation and length/displacement ratio. The data derived are very suitable for design applications and for the validation of theoretical analyses of ship wave resistance and wash waves

Solution combustion synthesis of calcium aluminate nanocomposite using coffee husk extract as green fuel and its application in adsorptive amputation of anionic dyes

Solution combustion synthesis of calcium aluminate (CaAl _2 O _4 ) nanocomposite using coffee husk extract and its adsorption capacity for removal of Congo red (CR) and Indigo carmine (IC) are reported. Physiochemical properties of adsorbent were studied by PXRD, SEM, TEM and point of zero charge. Batch adsorption studies were conducted to study the effect of adsorbent dosage, pH, contact time, initial dye concentration and temperature on adsorption efficiency of coffee husk derived calcium aluminate nanocomposite (CHCA). Among the isotherms used, Langmuir model explained best the equilibrium data and the maximum monolayer adsorption capacity was found to be 377 and 135 mg/g for CR and IC, respectively. Mass transfer analysis indicated adsorptive removal of dyes was controlled by both external and internal diffusion. Pseudo-first-order model fitted best with experimental kinetic data and adsorption efficiency increased with an increase in the initial bulk concentration of CR and IC. Thermodynamic analysis indicated that adsorption of CR and IC on CHCA is feasible, spontaneous and exothermic in nature. The magnitude of enthalpy and heat of adsorption suggested that the adsorption is physical in nature. The present study explores the potential of coffee husk extract, an agro-based bio-waste, as a novel and eco-friendly fuel in the synthesis of CHCA and the synthesised nanocomposite as a potential adsorbent for the removal of synthetic dyes

Carbon nanotubes and graphene-based materials for adsorptive removal of metal ions – A review on surface functionalization and related adsorption mechanism

Enhanced use of heavy metals for commercial and non-commercial applications has resulted in industrial and domestic discharge loaded with toxic metal ions creating increased environmental concern. Owing to the wide array of heavy metals that can be effectively removed, relatively low cost and economical process conditions, removal of heavy metals by adsorption has attracted the scientific community over years. Search for novel adsorbents which are cost-effective with higher adsorption affinity and reusability has been an area of active research. Carbon based adsorbents, which offer enhanced surface area, higher surface to volume ratio and ease of surface functionalization, have proven to be more effective than conventional adsorbents for removal of both inorganic and organic contaminants. Among the various carbon based adsorbents, carbon nanotubes, graphene and modified graphene oxide composites are gaining increasing importance as effective adsorbents for heavy metal removal from waste waters. This paper presents a comprehensive review on use of these adsorbents for adsorptive removal of various heavy metals. Optimal conditions for maximum removal of various metal ions are highlighted. Case studies on approach to surface functionalization of adsorbents and the mechanism of metal ion removal by the functionalized surface are discussed for practical application